Sibutril is the trade name of Sibutramine active substance, which helps people in losing weight. Sibutril anorexigenic effect is achieved by affecting CNS. Medication inhibits the reuptake of noradrenalin, serotonin and dopamine, stimulates the hypothalamus and suppresses appetite.
Sibutril therapeutic concentration is achieved in about 1-1.5 hours after medication intake. Anorexigenic effect after Sibutril single daily dose intake is maintained for approximately 14-16 hours. Sustained weight loss medication therapeutic effect is achieved on day 4 of the obesity treatment.
Sibutril is a supplement to dietary programs that include changing eating habits and regular physical activity. Anorexigenic medication is prescribed to people with a BMI greater than 30 and greater than or equal to 27 with associated diseases (e.g. diabetes, dyslipidemia and hypertension).
Sibutril weight loss medication is intended for the obesity treatment in adults and adolescents over 18 years.
- Elderly people and children under 18 years did not take part in clinical trials for Sibutril efficacy and safety. Therefore, Sibutril use is contraindicated to people younger than 18 and older than 65 years old.
Avoid using Sibutril during pregnancy and lactation, as well as the simultaneous use of MAO inhibitors and other CNS stimulating medications. On adding obesity related diseases medications in obesity therapy it is recommended to study Sibutril drug interactions.
Simultaneous Sibutril use with blood pressure lowering medication enhances the medication antihypertensive effect. Therefore, it is recommended to monitor blood pressure in combined therapy with Sibutril and antihypertensive medication.
In some cases, the daily dose of medication should be decreased for lowering the blood pressure.
The adipose tissue reduction during Sibutril treatment is accompanied by lipid profile and glycemic control improvement, and blood pressure stabilization. Thus, the use of Sibutril not only promotes weight loss, but also strengthens your overall health.
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